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In vivo T1-weighted 1H MR images of the brains of transgenic AD model (2xTg-AD, top) and wild-type (WT, bottom) mice at different depths, before and after injection of Gd-DOTA-based amyloid-targeted contrast agent Dyad-3. Red arrows indicate the amyloid-rich regions. Adapted with permission from [211]. Copyright 2021 American Chemical Society.
