Table 3. Summary of applied investigation results: The mean alcohol intake (g/day) with its interquartile interval, LACE estimate and 95% confidence interval (mmHg change in systolic blood pressure per 1 g/day increase in genetically-predicted alcohol intake) in each stratum using the residual method and doubly-ranked method.
IQR represents the interval for the interquartile range in each stratum. CI represents the 95% confidence interval.
| Stratum | Residual method | Doubly-ranked method | ||||
|---|---|---|---|---|---|---|
| Mean (IQR) | Estimate | 95% CI | Mean (IQR) | Estimate | 95% CI | |
| 1 | 0.13(0.00,0.24) | -5.14 | (-7.57,-2.70) | 0.27(0.00,0.45) | 0.32 | (-4.54,5.18) |
| 2 | 0.53(0.33,0.77) | -0.32 | (-1.05,0.41) | 0.67(0.24,1.03) | -0.87 | (-2.98,1.25) |
| 3 | 0.99(0.77,1.21) | 0.27 | (-0.39,0.94) | 1.10(0.65,1.51) | 0.16 | (-1.31,1.64) |
| 4 | 1.43(1.29,1.56) | 0.26 | (-0.43,0.95) | 1.54(1.03,1.93) | 0.98 | (-0.18,2.15) |
| 5 | 1.86(1.69,2.06) | 0.76 | (0.07,1.45) | 2.01(1.47,2.46) | 0.70 | (-0.25,1.64) |
| 6 | 2.40(2.21,2.60) | 1.30 | (0.64,1.96) | 2.56(1.83,3.09) | 1.31 | (0.54,2.08) |
| 7 | 3.11(2.89,3.35) | 0.58 | (-0.09,1.24) | 3.25(2.31,3.94) | 0.41 | (-0.21,1.03) |
| 8 | 4.05(3.71,4.40) | 1.22 | (0.58,1.87) | 4.19(3.09,5.09) | 1.15 | (0.64,1.67) |
| 9 | 5.54(5.09,6.04) | 1.41 | (0.75,2.07) | 5.67(4.00,6.86) | 1.31 | (0.91,1.71) |
| 10 | 10.16(7.60,11.41) | 1.07 | (0.67,1.46) | 8.96(5.86,10.91) | 0.91 | (0.65,1.17) |