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. 2023 Jul 4;28(13):5197. doi: 10.3390/molecules28135197

Table 1.

The effects of TAB derivatives against MI/R injury in H9c2.

Compd. Cell Viability (% of Control) clogP a
0 μM 0.5 μM 1 μM 2 μM 4 μM 8 μM
TAB 56.0 ± 0.7 60.2 ± 0.4 77.2 ± 1.1 68.6 ± 0.9 65.7 ± 0.6 65.5 ± 1.2 2.69
10 56.5 ± 1.3 58.2 ± 1.3 56.8 ± 0.9 62.5 ± 1.6 62.0 ± 0.8 59.5 ± 1.4 4.20
11 56.3 ± 0.8 60.5 ± 0.7 60.4 ± 0.6 61.7 ± 1.2 67.4 ± 0.5 64.3 ± 0.6 3.58
12a 56.6 ± 1.5 72.5 ± 0.5 75.7 ± 1.2 77.3 ± 1.5 74.6 ± 0.9 75.3 ± 1.1 3.99
12b 56.4 ± 0.5 68.6 ± 1.5 70.7 ± 1.4 73.8 ± 0.9 77.3 ± 1.1 70.6 ± 0.7 2.71
12c 56.7 ± 0.9 73.6 ± 0.5 78.5 ± 0.8 82.6 ± 1.1 80.4 ± 1.3 79.5 ± 0.8 3.48
12d 56.5 ± 0.5 71.0 ± 0.6 75.6 ± 1.1 74.6 ± 0.8 72.5 ± 1.6 59.6 ± 1.7 3.70
12e 56.1 ± 0.7 69.4 ± 1.2 74.1 ± 1.5 75.9 ± 1.2 73.7 ± 0.7 65.2 ± 0.3 2.64
12f 56.7 ± 0.3 63.3 ± 1.3 68.5 ± 0.6 68.3 ± 1.0 66.2 ± 1.6 60.9 ± 1.2 4.46
14a 56.9 ± 1.1 55.6 ± 1.0 57.4 ± 1.1 57.1 ± 1.4 59.7 ± 0.4 61.5 ± 1.1 4.62
14b 56.4 ± 1.4 58.4 ± 1.6 56.1 ± 1.2 57.4 ± 1.7 58.5 ± 1.8 62.5 ± 0.8 6.41
15 56.0 ± 1.2 60.3 ± 1.0 64.8 ± 0.5 71.8 ± 1.4 69.3 ± 1.1 63.9 ± 0.9 4.00
16a 55.8 ± 0.5 65.1 ± 0.6 65.7 ± 1.3 72.6 ± 0.3 70.8 ± 1.2 69.4 ± 0.5 5.30
16b 56.4 ± 0.8 67.3 ± 0.6 75.0 ± 1.2 72.5 ± 1.7 68.2 ± 0.9 66.3 ± 0.6 4.02
16c 56.2 ± 1.6 64.6 ± 1.5 72.4 ± 1.0 75.3 ± 1.2 69.3 ± 0.3 63.3 ± 0.5 4.79
16d 56.7 ± 0.5 69.5 ± 1.5 71.4 ± 0.6 72.9 ± 1.1 65.4 ± 0.8 67.2 ± 1.0 5.01

a clogP calculated by Molinspiration [35].