Skip to main content
. 2023 Jun 25;28(13):4979. doi: 10.3390/molecules28134979

Table 2.

The inhibition mechanism of different EOs against various fungus.

EOs Fungus Antifungal Mechanism
Chrysanthemum morifolium cv. Fubaiju EOs [42] C. albicans;
C. glabrata;
C. tropicalis;
S. cerevisiae;
D. hansenii;
Z. parabailii
  • (1)

    Biomacromolecules: mitochondrial and DNA damage [42];

  • (2)

    Cell wall/membrane integrity: plasma membrane disruption [42].

Cinnamon EOs [43] Mucor sp. FJ09;
Mucor circinelloides CNRMA 03.0371
  • (1)

    Spore/mycelial: destroys the mycelial morphology [43];

  • (2)

    Cell wall/membrane integrity: increases membrane permeability, leading to the leakage of cellular components [43].

  • (3)

    Metabolic level: increases reactive oxygen species content and alters soluble sugar and malondialdehyde content [43];

  • (4)

    Gene expression: upregulation expression of nox1 and nox2 genes [43];

Perilla frutescens EOs [44]
Foeniculum vulgare EOs [45]
Aspergillus flavus
Aflatoxin B1
  • (1)

    Spore/mycelial: affects spore development [44];

  • (2)

    Cell wall/membrane integrity: changes membrane permeability, leading to the leakage of biomacromolecules and ions [44,45]; changes mitochondrial membrane potential [45];

  • (3)

    Metabolic level: inhibits ATPase activity and increases the generation of ROS [44,45]; affects amino acid metabolism [44]; alters ergosterol content, C-sources utilization, and Nor-1 gene expression [45].

Cleome viscosa EOs [46]
Aegle marmelos L. Corrêa EOs [47]
Candida albicans
  • (1)

    Cell wall/membrane integrity: reduces the chitin levels and interferes with cell wall biosynthesis [46]; binds to ergosterol in the membrane and results in ion permeability increase [47].

Tea tree EOs [48]
Monarda didyma L. EOs [49]
Alternaria solani
  • (1)

    Spore/mycelial: affects mycelial growth [48,49].

  • (2)

    Metabolic level: increases the peroxidase and phenylalanine ammonialyase activities [48].

Monarda didyma L. EOs [49] Colletotrichum sp.
  • (1)

    Spore/mycelial: affects mycelial growth [49].