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The effects of a HFD on the survival rate in ACR-treated mice at ZT0 and ZT12. A total of 40 mice were randomly divided into 4 groups. The control mice and the HFD-fed mice were treated with 100 mg/kg ACR by means of intragastric administration at ZT0 or ZT12. The survival rate is shown for the four groups of mice after treatment with 100 mg/kg ACR at ZT0 and ZT12 for 48 h (n = 10/group).
