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Trastuzumab antibody-functionalized iodinated and non-iodinated heptacyanines prepared by Kobzev et al. [259] for photoimmunotherapy. The structural combination with the antibody (pink) contributed to the immunotherapeutic activity of the dyes; the sulfonyl groups (green) made the cyanines more biocompatible; and the iodine atoms (red) allowed an increase in the production of singlet oxygen.
