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. 2023 Jun 28;28(13):5053. doi: 10.3390/molecules28135053

Figure 2.

Figure 2

The effect of Rhodiola rosea L. extract administered alone or in combination with MTX on hind paw volume (HPV) on days 14 and 21. HC—control animals, AA—adjuvant arthritis untreated control, MTX—adjuvant arthritis group treated with methotrexate 0.3 mg/kg of b.w. twice a week, RS—adjuvant arthritic animals treated by Rhodiola rosea L. extract 150 mg/kg daily, RS-MTX—adjuvant arthritic animals treated with RS (150 mg/kg) daily and 0.3 mg/kg of b.w. twice a week. The results were expressed as mean ± SEM, n = 6–8. Significant difference: + p < 0.05 AA vs. HC, * p < 0.05 treated group vs. AA, and # p > 0.05 RS-MTX vs. MTX.