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. 2023 Jun 28;28(13):5053. doi: 10.3390/molecules28135053

Figure 4.

Figure 4

The effect of Rhodiola rosea L. extract administered alone or in combination with MTX on the level of MMP9 in plasma was measured on days 14 and 21. HC—control animals, AA—adjuvant arthritis controls, AA-MTX—adjuvant arthritis group treated with methotrexate 0.3 mg/kg of b.w. twice a week, AA-RS—adjuvant arthritic animals treated with Rhodiola rosea L. extract 150 mg/kg daily, RS-MTX—adjuvant arthritic animals treated with RS (150 mg/kg) daily and 0.3 mg/kg of b.w. twice a week. Results were expressed as mean ± SEM, n = 6–7. Significant difference: + p < 0.05 AA vs. HC, * p < 0.05 treated group vs. AA.