Table 1.

Gut microbiota dysbiosis in acute pancreatitis compared with healthy controls.

Studies	Subjects	Sample	Phylum	Genus	Species
Tian 2015 [29]	76 AP and 32 HC	Fecal		Enterobacteriaceae ↑ Enterococcus ↑ Bifidobacterium ↓
Zhang 2018 [17]	45 AP and 44 HC	Fecal	Bacteroidetes ↑ Proteobacteria ↑ Firmicutes ↓ Actinobacteria ↓
Zhu 2019 [18]	130 AP and 35 HC	Fecal	Proteobacteria ↑ Bacteroidetes ↓	Escherichia/Shigella ↑ Enterococcus ↑ An unknown genus in family of Enterobacteriaceae ↑ Prevotella_9 ↓ Faecalibacterium ↓ Blautia ↓ Lachnospiraceae ↓ Bifidobacterium ↓
Yu 2020 [23]	60 AP and 20 HC	Rectal swab		Finegoldia ↑ Anaerococcus ↑ Enterococcus ↑ Eubacterium hallii ↓	Blautia ↓ Finegoldia ↑
van den Berg 2021 [30]	35 AP and 15 HC	Fecal	Proteobacteria ↑	Escherichia/Shigella ↑ Streptococcus ↑ Butyrate producers ↓ 1

AP, acute pancreatitis; HC, health controls. The arrows indicate the alteration of gut microbiota in AP compared with healthy controls. ¹ A panel of butyrate producers based on genus taxonomy was constructed based on butyrate-producing taxa (Alistipes, Anaerostipes, Butyricicoccus, Butyricimonas, Butyrivibrio-010, Coprococcus_1, Coprococcus_2, Coprococcus_3, Eubacterium, Faecalibacterium, Flavonifractor, Odoribacter, Oscillibacter, Pseudoflavonifractor, Roseburia, Ruminococcus_2, Subdoligranulum).