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. 2023 Jun 29;14:1089956. doi: 10.3389/fgene.2023.1089956

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Copyright © 2023 Frascarelli, Zanetti, Nasca, Izzo, Lamperti, Lamantea, Legati and Ghezzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circos plot visualization using Circos plots for control samples (ctrl1, ctrl2, and ctrl3) and samples carrying multiple mtDNA deletions (multidel1, multidel2, multidel3, and multidel4) sequenced using the Rapid kit. Black lines indicate the deletions and link the coordinates of deletion breakpoints. For sample multidel1 (sequenced on the Flow Cell R.9.4.1), lines thickness is proportional to the number of reads containing the deletion. Under each graph, flow cell type and average depth of coverage are indicated (R9 = Flow cell R9.4.1).