Table 2.
Primary and Secondary Outcomes by Resuscitation Type
| Outcomes | LTOWB (n = 624) |
COMPONENT (n = 427) |
Unadjusted | Adjusted* | ||||
|---|---|---|---|---|---|---|---|---|
| RR | 95% CI | p Value | RR | 95% CI | p Value | |||
| Primary | ||||||||
| 4-h mortality† | 50 (8.2) | 32 (7.5) | 1.09 | (0.71–1.66) | 0.70 | 0.90 | (0.59–1.39) | 0.64 |
| TBI subgroup | 6 (6.4) | 2 (4.5) | 1.40 | (0.29–6.68) | 0.67 | 0.61 | (0.14–2.70) | 0.51 |
| Secondary | ||||||||
| 24-h mortality | 82 (13.4) | 49 (11.5) | 1.16 | (0.83–1.62) | 0.37 | 1.08 | (0.77–1.52) | 0.67 |
| TBI subgroup | 19 (20.2) | 6 (13.6) | 1.48 | (0.64–3.45) | 0.36 | 0.89 | (0.41–1.96) | 0.78 |
| 28-d mortality | 110 (17.9) | 66 (15.5) | 1.16 | (0.88–1.53) | 0.30 | 1.10 | (0.83–1.47) | 0.51 |
| TBI subgroup | 25 (26.6) | 11 (25.0) | 1.06 | (0.58–1.96) | 0.84 | 0.84 | (0.45–1.56) | 0.57 |
*
Adjusted for age, sex, injury type, head Abbreviated Injury Scale score, prehospital hypotension, receiving any prehospital blood product, and Injury Severity Score.
†
The adjusted model is weighted by the inverse probability of treatment (propensity score).
COMPONENT, blood component resuscitation; LTOWB, low-titer group O whole blood; RR, relative risk; TBI, traumatic brain injury.