Table 2.
Primary and Secondary Outcomes by Resuscitation Type
Outcomes | LTOWB (n = 624) |
COMPONENT (n = 427) |
Unadjusted | Adjusted* | ||||
---|---|---|---|---|---|---|---|---|
RR | 95% CI | p Value | RR | 95% CI | p Value | |||
Primary | ||||||||
4-h mortality† | 50 (8.2) | 32 (7.5) | 1.09 | (0.71–1.66) | 0.70 | 0.90 | (0.59–1.39) | 0.64 |
TBI subgroup | 6 (6.4) | 2 (4.5) | 1.40 | (0.29–6.68) | 0.67 | 0.61 | (0.14–2.70) | 0.51 |
Secondary | ||||||||
24-h mortality | 82 (13.4) | 49 (11.5) | 1.16 | (0.83–1.62) | 0.37 | 1.08 | (0.77–1.52) | 0.67 |
TBI subgroup | 19 (20.2) | 6 (13.6) | 1.48 | (0.64–3.45) | 0.36 | 0.89 | (0.41–1.96) | 0.78 |
28-d mortality | 110 (17.9) | 66 (15.5) | 1.16 | (0.88–1.53) | 0.30 | 1.10 | (0.83–1.47) | 0.51 |
TBI subgroup | 25 (26.6) | 11 (25.0) | 1.06 | (0.58–1.96) | 0.84 | 0.84 | (0.45–1.56) | 0.57 |
Adjusted for age, sex, injury type, head Abbreviated Injury Scale score, prehospital hypotension, receiving any prehospital blood product, and Injury Severity Score.
The adjusted model is weighted by the inverse probability of treatment (propensity score).
COMPONENT, blood component resuscitation; LTOWB, low-titer group O whole blood; RR, relative risk; TBI, traumatic brain injury.