Table 5.
Subgroup analysis of D-dimer.
| Characteristics | Number of literatures | OR (95% CI) | P | I2 (%) |
|---|---|---|---|---|
| Overall | 11 | 16.90 (8.57, 33.34) | <.001 | 74.7 |
| Bias | ||||
| High | 5 | 17.57 (4.85, 63.73) | <.001 | 80.5 |
| Not high | 6 | 18.49 (9.38, 36.45) | .040 | 57.0 |
| Country | ||||
| China | 9 | 12.88 (6.72, 24.68) | <.001 | 72.8 |
| Overseas | 2 | 160.39 (32.04, 802.94) | .782 | 0.0 |
| Threshold | ||||
| Traditional threshold | 7 | 9.37 (4.62, 18.99) | .014 | 62.3 |
| Age-corrected threshold | 4 | 42.30 (15.25, 117.38) | .038 | 64.3 |
| Disease | ||||
| PE | 9 | 13.90 (6.53, 29.57) | .001 | 70.8 |
| ATPE | 2 | 34.93 (6.74, 181.12) | .019 | 81.9 |
| Gold standard | ||||
| Clinical | 5 | 9.84 (5.48, 17.67) | .251 | 25.6 |
| CTPA | 6 | 32.59 (9.77, 108.79) | <.001 | 84.7 |
CI = confidence interval, CTPA = computed tomography pulmonary angiography, I2 = I-square test.