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. 2023 Jun 10;26(7):107095. doi: 10.1016/j.isci.2023.107095

Figure 2.

Figure 2

Correlation analyses of TCGA mRNA data for CD8+ T cell-related immune and viral defense markers

(A) Heatmap of TCGA LUAD, n = 510 (top panel) and LUSC, n = 484 (bottom panel) RNAseq data derived Spearman correlations between TIMER 2.0 immune deconvolution inferred abundance and normalized counts for targeted interferon gene panel. Color scale based on Z score.

(B) TCGA LUSC forest plot, panel markers vs. CD8A, Pearson correlation (r with 95% confidence interval). ∗ indicates an adjusted p value less than 0.05 after FDR 0.05 multiple comparisons correction two-stage linear step-up procedure of Benjamini, Kriegerm, and Yekutieli.

(C) TCGA LUAD forest plot, panel markers vs. CD8A, Pearson correlation (r with 95% confidence interval). ∗ indicates an adjusted p value less than 0.05 after FDR 0.05 multiple comparisons correction two-stage linear step-up procedure of Benjamini, Kriegerm, and Yekutieli.