IHC-based correlation analyses in NSCLC tumor biopsy validation cohort
(A) H-score-based Spearman’s rank correlation similarity matrix, one minus Spearman’s rank correlation-based clustering (n = 63).
(B) H-score-based correlation forest plot for panel markers vs. CD8α H-score, Spearman’s rank correlation (rho with 95% confidence interval depicted). ∗ indicates an adjusted p value less than 0.05 after FDR 0.05 multiple comparisons correction two-stage linear step-up procedure of Benjamini, Kriegerm, and Yekutieli (n = 63).
(C) H-score-based correlation forest plot for panel markers vs. CD8α infiltration score Spearman’s rank correlation (rho with 95% confidence interval depicted). ∗ Indicates adjusted p value less than 0.05 after FDR 0.05 multiple comparisons correction two-stage linear step-up procedure of Benjamini, Kriegerm, and Yekutieli (n = 63).