Table 1.
Demonstrates the structure, ionicity, stability, osmolality, viscosity, Log Ktherm, Log Kcond, and T1/2 of various gadolinium contrast agents.
| Gd-EOB-DTPA | Gd-DTPA-BMA | Gd-DTPA-BMEA | Gd-HP-DO3A | Gd-BOPTA | Gd-DO3A-butrol | Gd-DOTA | Gd-DTPA | |
|---|---|---|---|---|---|---|---|---|
| Structure | Linear | Linear | Linear | Macrocyclic | Linear | Macrocyclic | Macrocyclic | Linear |
| Ionicity | ionic | Nonionic | Nonionic | Nonionic | ionic | Nonionic | ionic | ionic |
| Stability | Intermediate | Low | Low | High | Intermediate | Intermediate | High | Intermediate |
| Osmolality | 688 | 789 | 110 | 630 | 1970 | 1603 | 1350 | 1960 |
| Viscosity | 12 | 1.4 | 2 | 1.3 | 5.3 | 5 | 2 | 2.9 |
| Log Ktherm | 23.5 | 16.9 | 16.6 | 23.8 | 22.6 | 21.8 | 25.6 | 22.1 |
| Log Kcond | 18.7 | 14.9 | 15 | 17.1 | 18.4 | 14.7 | 19.3 | 17.7 |
| T1/2 | < 5 s | < 5 s | < 5 s | 3.9 h | < 5 s | 43 h | 338 h | < 5 s |