Table 2.
CricRNA | Cancer types | Mechanisms | Roles | References |
---|---|---|---|---|
cricCDDC66 | Colon cancer | miRNA sponge | OG | [22] |
cricHIPK3 | Bladder cancer | miRNA sponge | TS | [22] |
cricPCNXL2 | Kidney cancer | miR-153sponge | OG | [23] |
hsa_circ_001895 | Kidney cancer | miR-296-5p sponge | OG | [23] |
cric-AKT3 | Kidney cancer | miR-296-3p sponge | TS | [23] |
cricANRIL | Breast, bladder and gastric cancer | Impairs ribosome biogenesis leading to p53 activation | OG | [33, 99] |
cricRNA_0000285 | Cervical cancer |
Upregulation of FUS increases CC proliferation and metastasis |
OG | [90] |
circRNA WHSC1 | Endometrial and ovarian cancer |
miR-646 sponge,miR-145 sponge, miR-1182 sponge |
OG | [91, 92] |
circURI1 | Gastric cancer | Directly interacts with heterogeneous ribonucleoproteins to inhibit GC transfer | TS | [93, 94] |
hsa_circ_001783 | breast cancer | miR-20c-3p sponge | OG | [95] |
FUS A ubiquitously expressed protein belonging to a family of heterogeneous nuclear proteins that plays important roles in DNA damage, cellular stress responses, RNA metabolism and processing. MiRNA sponge: It is a competitive inhibitor of miRNA, which can adsorb the corresponding miRNA and compete with miRNA target genes