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. 2023 Jul 13;14:128. doi: 10.1007/s12672-023-00728-w

Table 3.

Other lncRNA and cancer

LncRNA Cancer types Mechanism Roles References
GAS5 Breast cancer, glioblastoma, SCC Affects GR signaling ,interacts with miRNA, reduces cell proliferation and increase apoptosis TS [22, 33]
LUNAR1 T-ALL Activation of IGF1R expression in cis cells to regulate T cell growth OG [33]
NEAT1 Liver and ovarian cancer, melanoma It is a target gene of P53 and can activate oncogenes OG [33]
LUCAT1 Kidney cancer Promoting proliferation and invasion of clear cell renal cell carcinoma via AKT/GSK-3β signaling pathway OG [100]
GAS6-AS2 Bladder cancer Induction of G1 arrest promotes tumor growth, and miR-298 sponge regulates CDK9 expression. OG [103]
FOXD2-AS1 Gastric cancer Promote cell cycle progression and accelerate cell proliferation OG [104]
lncRNA-p21 Rectal cancer Involved in the transcriptional regulation of P21 and P53 TS [33]
NAMA PTC Regulated by the MAP pathway TS [113]
PTCSC3 PTC Inhibit the expression of S100A4, VEGF and MMP9,inhibit the growth and invasion of TC cells TS [113]

T-ALL T cell acute lymphoblastic leukemia, SCC squamous cell carcinoma, PTC papillary thyroid cancer, TC thyroid cancer