Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 13;14(7):418. doi: 10.1038/s41419-023-05954-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — A Gene profile changes in the lungs of IL-10 ^B-WT and IL-10 ^B-KO mice, analyzed by RNA-seq (n = 6). B Heatmap showing the top 20 up and down-regulated gene expression of the lung in IL-10 ^B-WT and IL-10 ^B-KO mice (n = 6). C Gene expression of the neutrophil-associated chemokines Gpr35, Cxcl15, Ccl5, Ccr2, and the macrophage activation-associated negative regulator Klf2. D, E KEGG and GO enrichment analysis. F Cytoscape analysis of the gene interactions network, algorithm of the network structure, and calculation of the weighted linkage between nodes to filter out the vital hub genes. G Expression levels of hub genes in the lung tissues of IL-10 ^B-WT and IL-10 ^B-KO mice (n = 6). Student’s t-test was used for the statistical analyses.