Table 1.
Clinical characteristics of patient cohorts.
| Cohort: | Patients |
|---|---|
| N | 9 |
| Demographics: | |
| Age (year) | 73.25 ± 6.16 |
| Sexy (Male/Female) | 2/7 |
| Underlying medical comorbidities, N (%) | |
| Hypertensive disease | 5(55.6) |
| Diabetes mellitus | 3(33.3) |
| Coronary artery disease or congestive heart failure or myocardial infarction | 4(44.4) |
| Chronic lung disease | 6(66.7) |
| Cerebral infarction or Mental disorder | 5(55.6) |
| Chronic kidney diseasea | 0 |
| Clinical information on day of enrollment: | |
| Hours from hospital arrival to enrollment | 20.06 ± 12.02 |
| Hours from initial antibiotic initiation | 3.39 ± 1.24 |
| Documented T ≥ 37 °C, N (%) | 9(100) |
| Documented SBP < 90 mmHg, N (%) | 7(77.8) |
| Vasopressor therapy within 48 h, N (%) | 5(55.6) |
| SOFA scoreb | 8.22 ± 2.05 |
| Oxygenation index | 156.22 ± 61.24 |
| ARDS classificationc, (N) | |
| Mild | 2 |
| Moderate | 5 |
| Severe | 2 |
| Clinical lab index: | |
| WBC Count (*109/L) | 23.37 ± 13.52 |
| % Neutrophil | 101.23 ± 40.72 |
| % Lymphocytes | 7.09 ± 5.51 |
| % Monocytes | 13.56 ± 28.07 |
| C reactive protein (mg/l) | 118.92 ± 91.78 |
| Procalcitonin, PCT (ng/ml) | 3.14 ± 2.89 |
| Serum lactate (mmol/dL) | 3.66 ± 1.96 |
| Endotracheal intubation, N (%) | 6(66.7) |
| Duration of mechanical ventilation (hours) | 108.50 ± 71.86 |
| Clinical outcomes variables: | |
| ICU stays (days) | 15.67 ± 6.16 |
| Death during index illness and/or hospitalization, N (%) | 2(22.2) |
| Second hospital admission within 30 days, N (%) | 1(14.3) |
| Mortality(90-day), N (%) | 3(33.3) |
All continuous values were expressed as mean ± SD.
aTips: Chronic kidney disease greater than stage 3, its glomerular filtration rate <60 ml /min.
bSequential Organ Failure Assessment (SOFA) score was performed on the day of admission, scoring criteria for assessing disease severity based on the functional status of six organ systems.
cBerlin criteria for the diagnosis of ARDS in adults.