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. 2023 Jul 13;14(7):424. doi: 10.1038/s41419-023-05953-3

Fig. 8. Model for the TM4SF1-AS1-induced stress adaptation.

Fig. 8

In the early steps of gastric tumorigenesis, TM4SF1-AS1 is transcriptionally activated. TM4SF1-AS1 sequesters RACK1 within SGs, which leads to suppression of stress-responsive MAPK signaling and inhibition of apoptosis (created with BioRender.com).