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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Alzheimers Dement. 2023 Jan 14;19(7):2923–2932. doi: 10.1002/alz.12912

Table 2.

Biomarker association with baseline age (regression parameter (standard error (SE) in each cell) and their cross-sectional comparisons across groups (last column)

DIAN MC
(n=33)		 ACS FH+
(n=176)		 DIAN NON MC
(n=58)		 ACS FH−
(n=120)		 P-values for Comparisons
CSF Aβ42
(pg/mL)		 −26.24 (22.02)
*p=0.2343		 −16.13 (9.14)
*p=0.0787		 −25.11 (14.64)
*p=0.0873		 −13.46 (11.96)
*p=0.2613		 Non-sig
CSF Tau
( pg/mL)		 2.88 (2.50)
*p=0.2510		 2.15 (1.05)
*p=0.0412		 1.48 (1.70)
*p=0.3834		 2.07 (1.37)
*p=0.1298		 Non-sig
CSF pTau181
( pg/mL)		 0.46 (0.25)
*p=0.0742		 0.24 (0.11)
*p=0.0284		 0.14 (0.17)
*p=0.4095		 0.25 (0.14)
*p=0.0741		 Non-sig
PiB MCSUVR 0.05 (0.01)
*p=<0.0001		 0.01 (0.01)
*p=0.0267		 0.01 (0.01)
*p=0.2533		 0.01 (0.01)
*p=0.1666		 0.0063; 0.0061;
0.0062
MRI Hippocampal Volume
(mm3)		 −16.43 (25.48)
*p=0.5195		 −25.66 (10.56)
*p=0.0156		 −27.59 (17.11)
*p=0.1078		 −29.79 (14.16)
*p=0.0362		 Non-sig
MRI Cortical Thickness
(mm)		 −0.02 (0.01)
*p=0.0120		 −0.01 (0.003)
*p=0.0121		 0.01(0.01)
*p=0.0870		 −0.01 (0.004)
*p=0.0041		 0.0026; 0.0064;
0.0022
Cognition −0.01 (0.02)
*p=0.5216		 −0.02 (0.01)
*p=0.0048		 −0.02 (0.01)
*p=0.1393		 −0.02 (0.01)
*p=0.0081		 Non-sig
1=

DIAN MC vs. ACS FH+;

2=

DIAN MC vs. DIAN NON MC;

3=

DIAN MC vs. ACS FH−;

4=

ACS FH+ vs. DIAN NON MC;

5=

ACS FH+ vs. ACS FH−;

6=

DIAN NON MC vs. ACS FH−

*

P-value for testing whether each regression parameter equals to 0.