Table 1.
Method | Mechanism | Role |
---|---|---|
Original | CWA-APTT CWA-PT CWA-TT |
Intrinsic pathway Extrinsic pathway Fibrinogen |
Modified | CWA-PT with APTT CWA-dPT using PRP (sTF/FIXa) CWA-dTT CFWA |
Intrinsic and extrinsic pathways Intrinsic and extrinsic pathways, thrombin burst Fibrinogen, thrombin burst Coagulation and fibrinolysis |
Abbreviations: CWA, clot waveform analysis; APTT, activated partial thromboplastin time; PT, prothrombin time; TT, thrombin time, dPT, dilute PT; dTT, dilute TT; PRP, platelet-rich plasma; sTF/FIXa, small amount of tissue factor-induced clotting factor IX activation; CFWA, clot-fibrinolysis waveform analysis