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. 2023 Jun 30;43(6):531–538. doi: 10.3343/alm.2023.43.6.531

Table 1.

Original and modified CWA

Method Mechanism Role
Original CWA-APTT
CWA-PT
CWA-TT
Intrinsic pathway
Extrinsic pathway
Fibrinogen
Modified CWA-PT with APTT
CWA-dPT using PRP
(sTF/FIXa)
CWA-dTT
CFWA
Intrinsic and extrinsic pathways
Intrinsic and extrinsic pathways,
thrombin burst
Fibrinogen, thrombin burst
Coagulation and fibrinolysis

Abbreviations: CWA, clot waveform analysis; APTT, activated partial thromboplastin time; PT, prothrombin time; TT, thrombin time, dPT, dilute PT; dTT, dilute TT; PRP, platelet-rich plasma; sTF/FIXa, small amount of tissue factor-induced clotting factor IX activation; CFWA, clot-fibrinolysis waveform analysis