TABLE 7.
Extracts and fractions of proanthocyanidins with different IC50 from A. melanocarpa (Michx.) Ell.
| Yield (mg) | Content (mg/100 g FW) | mDP | IC50 values (μg/mL) | |||
|---|---|---|---|---|---|---|
| α‐Amylase (Worsztynowicz et al., 2014) | α‐Glucosidase (Bräunlich et al., 2013) | Lipase | ||||
| Crude Proanthocyanidins extract (CPE) | 29678.6 ± 30.5 | 1483.9 ± 1.5 | 49.3 ± 3.8 | 1.16 ± 0.12 | 0.81 ± 0.15 | 1.79 ± 0.06 |
| Crude oligomer fraction from CPE (COF) | 6618.5 ± 36.6 | 330.9 ± 1.8 | 1.8 ± 0.5 | – | – | – |
| Monomers | 446.1 ± 26.0 | 22.3 ± 1.3 | – | – | – | – |
| Oligomers without monomers (OWM) | 6072.0 ± 22.1 | 303.6 ± 3.1 | 4.2 ± 0.9 | 4.32 ± 0.21 | 3.99 ± 0.42 | 5.03 ± 0.55 |
| Crude polymerized proanthocyanidins (CPP) | 22906.4 ± 28.9 | 1145.3 ± 1.4 | 56.9 ± 2.5 | 1.01 ± 0.06 | 0.75 ± 0.03 | 1.61 ± 0.02 |
| CPP‐50 | 6546.8 ± 24.5 | 327.3 ± 1.2 | 78.9 ± 4.1 | 0.23 ± 0.01 | 0.15 ± 0.06 | 0.31 ± 0.13 |
| CPP‐60 | 8248.0 ± 21.6 | 412.4 ± 1.1 | 66.1 ± 1.2 | 0.83 ± 0.05 | 0.72 ± 0.02 | 1.57 ± 0.06 |
| CPP‐70 | 3956.0 ± 30.1 | 197.8 ± 1.5 | 36.8 ± 3.9 | 1.39 ± 0.02 | 0.98 ± 0.03 | 2.05 ± 0.20 |
| CPP‐75 | 1814.2 ± 27.3 | 90.7 ± 1.4 | 25.2 ± 1.3 | 2.46 ± 0.05 | 1.41 ± 0.04 | 3.03 ± 0.11 |
| CPP‐L | 2052.1 ± 24.4 | 102.6 ± 1.2 | 10.2 ± 2.6 | 3.01 ± 0.01 | 2.56 ± 0.05 | 4.56 ± 0.31 |
Abbreviation: – not determined.