Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 31;7(14):3339–3349. doi: 10.1182/bloodadvances.2022009307

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Figure 2. — ERFE overexpression does not alter blood erythrocyte parameters in adult thalassemic mice. Mice generated from Th3 × E(M) breedings were analyzed at 16 weeks. Measurements in males are depicted in closed circles and females in open circles. (A-C) Erythroferrone levels were assessed by (A) BM Erfe mRNA, (B) spleen Erfe mRNA levels, (C) serum ERFE. (D) Serum EPO. (E-J) Erythrocyte parameters: (E) Hb levels, (F) RBC count, and (G) hematocrit. (H-J) Body and organ weights: (H) total body weight, (I,J) liver and spleen weights as a percentage of total body weight. P values were assessed by two-tailed unpaired t test (∗∗P < .01, ∗∗∗P < .001, ∗∗∗∗P < .0001) between the Th3 and T-E(M) groups only and (A-C) also between E(M) and T-E(M).