Skip to main content
. 2023 Apr 17;7(14):3416–3430. doi: 10.1182/bloodadvances.2022008327

Table 1.

List of CCR4-CARs and their original mAbs

# CAR scFv mAb clone Affinity (Kd) CCR4 epitope Reference
1 KW_H2L H to L KW-0761 ND (slow dissociation) NT 12 to 29 (DESIYSNYYLYESIPKPC) 11
2 KW_L2H L to H
3 1-49_H2L H to L mAb 1-49 77.98 nM ND (combinatorial of NT and ECL) 29
4 1-49_L2H L to H
5 2-3_H2L H to L mAb 2-3 1.39 nM
6 2-3_L2H L to H
7 h1567_H2L H to L h1567 2.54 nM
8 h1567_L2H L to H

Kd values are from data as antibodies but not as scFvs.

ECL, extracellular loop; ND, not determined; NT, N-terminus.