Table 5.
Differences between patients with or without osteoporosis or bone microarchitecture degradation
| Variables | With osteoporosis or bone microarchitecture degradation | Without osteoporosis or bone microarchitecture degradation | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
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| Sample (N=109) | Osteoporosis (T-score ≤−2.5) | P-value | Sample (N=57) | Bone degradation (TBS <1.230) | P-value | |||
|
|
|
|||||||
| Yes (N=17) | No (N=92) | Yes (N=13) | No (N=44) | |||||
| Age (yr) | 58.0 (53.0–61.0) | 59.0 (53.5–63.5) | 57.0 (53.0–61.0) | 0.128a) | 58.0 (54.0–61.5) | 59.0 (57.0–63.5) | 57.5 (53.0–61.0) | 0.107a) |
|
| ||||||||
| Length of hospital stay (days) | 20.0 (11.0–32.0) | 24.0 (10.0–44.8) | 20.0 (11.0–31.0) | 0.247a) | 22.0 (12.0–34.0) | 32.5 (14.0–36.5) | 20.0 (11.0–33.0) | 0.182a) |
|
| ||||||||
| HbA1c (%) | 6.4 (5.8–8.4) | 6.1 (5.7–7.2) | 6.5 (5.8–8.8) | 0.316a) | 6.4 (5.9–8.3) | 6.4 (5.7–8.3) | 6.3 (5.9–8.3) | 0.739a) |
|
| ||||||||
| eGFR (mL/min/1.73 m2) | 78.1 (47.5–97.7) | 89.9 (48.2–100.4) | 73.0 (45.3–96.9) | 0.381a) | 79.8 (58.0–100.0) | 60.5 (31.7–95.7) | 86.4 (60.7–100.0) | 0.159a) |
|
| ||||||||
| 25(OH)D (ng/mL) | 23.1 (17.8–30.7) | 21.6 (15.1–28.6) | 23.1 (18.1–30.8) | 0.659a) | 22.3 (18.1–27.1) | 19.1 (15.1–29.4) | 22.6 (18.5–26.4) | 0.610a) |
|
| ||||||||
| PTH (pg/mL) | 36.0 (26.5–63.2) | 62.5 (37.2–119.0) | 34.2 (25.0–54.1) | 0.016a) | 30.9 (24.0–54.2) | 44.3 (33.4–104.0) | 28.0 (21.2–49.8) | 0.024a) |
|
| ||||||||
| LVEF (%) | 48.0 (34.0–60.0) | 31.0 (25.0–60.0) | 48.0 (35.3–60.0) | 0.086a) | 54.0 (34.0–60.5) | 40.0 (30.0–57.5) | 56.0 (34.3–61.8) | 0.313a) |
|
| ||||||||
| BMI (kg/m2) | 28.3±5.4 | 23.2±4.4 | 29.2±5.0 | <0.001b) | 28.6±5.4 | 27.6±4.8 | 28.9±5.6 | 0.443b) |
|
| ||||||||
| TBS | 1.362 (1.261–1.431) | 1.201 (1.063–1.279) | 1.368 (1.293–1.435) | 0.013a) | ||||
|
| ||||||||
| T-score LS | −0.867±1.587 | −2.015±1.520 | −0.527±1.455 | 0.002b) | ||||
|
| ||||||||
| T-score FN | −0.895±1.163 | −1.654±1.124 | −0.670±1.088 | 0.006b) | ||||
|
| ||||||||
| T-score TF | −0.400±1.291 | −1.131±1.447 | −0.113±1.160 | 0.011b) | ||||
a)
Mann–Whitney U test.
b)
Student’s t-test.
HbA1c, hemoglobin A1c; eGFR, estimated glomerular filtration rate; 25(OH)D, 25-hydroxy-vitamin D; PTH, parathyroid hormone; LVEF, left ventricular ejection fraction; BMI, body mass index; TBS, trabecular bone score; LS, lumbar spine; FN, femoral neck; TF, total femur.