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. 2023 Jun 8;7(1):e147. doi: 10.1017/cts.2023.572

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© The Author(s) 2023

This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.

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Figure 3. — The interrelated activities of a learning health system (LHS) adapting to the new NIH Data Management and Sharing Policy necessitate behavioral adjustments, which are fostered through education, to promote compliance. LHS roles, depicted by the CTS Personas, highlight new aspects of essential knowledge and behaviors that should be considered in creating educational resources and new approaches to their work. Education, policy, behavior, and compliance are numbered 1–4, respectively, in the diagram, corresponding to four subsections below detailing the use case. Abbreviation Key: AI/ML, Artificial Intelligence/Machine Learning Researcher Persona profile; CenterAdmin, Clinical Research Center Administrator Persona profile; CHE, Community Health Educator Persona profile; CRC, Clinical Research Coordinator Persona profile; DataAnalyst, Data Analyst Persona profile; Developer, Developer Persona profile; Ethicist, Research Ethics and Bioethics Expert Persona profile; Librarian, Librarian Persona profile; LHS, Learning Health System; MedEd, Medical Education Coordinator Persona profile; Researcher, includes all Researcher Persona profiles: Basic Scientist, Community-Engaged Researcher, K Scholar, Physician Scientist, Research Ethics and Bioethics Expert, Artificial Intelligence/Machine Learning Researcher; RA, Research Administrator Persona profile; Senior IRB, Senior IRB and Regulatory Manager Persona profile.