Table 1.

Background of the study participants.

(Unit)		MSM Group	Placebo Group	p Value 1	MSM Group	Placebo Group	p Value 1
		(n = 39)	(n = 41)		(n = 44)	(n = 44)
Sex	female/male	28/11	30/11	1.000	31/13	32/12	1.000
K-L grade	grade 1/grade 0	14/25	17/24	0.652	18/26	17/27	1.000
Age	Mean ± SD	48.9 ± 13.7	48.9 ± 13.8	0.988	49.3 ± 13.7	49.2 ± 13.7	0.975
(years)	Med	52.0	48.0		52.0	47.5
	Min–Max	26–85	23–80		26–85	23–80
	Mean ± SD	161.5 ± 7.5	163.1 ± 7.7	0.335	161.9 ± 7.8	163.2 ± 7.5	0.424
Height	Med	161.00	161.00		161.00	161.00
(cm)	Min–Max	144.0–174.0	148.5–180.0		144.0–188.0	148.5–180.0
Weight	Mean ± SD	62.0 ± 15.8	60.7 ± 13.8	0.686	61.8 ± 15.7	60.3 ± 13.6	0.631
(kg)	Med	59.50	61.10		59.30	59.75
	Min–Max	44.3–117.5	36.1–93.7		43.2–117.5	36.1–93.7
BMI	Mean ± SD	23.6 ± 5.2	22.6 ± 4.3	0.354	23.4 ± 5.0	22.5 ± 4.2	0.353
(kg/cm2)	Med	22.40	21.40		22.60	21.40
	Min–Max	18.4–42.6	16.4–36.6		17.5–42.6	16.4–36.6
PBF	Mean ± SD	29.1 ± 10.0	27.9 ± 9.6	0.605	28.3 ± 9.7	27.6 ± 9.7	0.732
(%)	Med	26.90	26.30		26.80	25.85
	Min–Max	13.4–58.8	12.7–55.5		13.4–58.8	12.7–55.5
Systolic BP	Mean ±S D	119.9 ± 11.2	118.8 ± 16.4	0.716	121.3 ± 12.5	119.0 ± 16.7	0.480
(mmHg)	Med	117.0	112.0		117.5	112.5
	Min–Max	103–149	90–159		103–157	90–159
Diastolic BP	Mean ± SD	77.8 ± 7.8	76.7 ± 11.5	0.628	78.1 ± 8.9	76.8 ± 11.5	0.541
(mmHg)	Med	76.0	73.0		76.0	73.5
	Min–Max	66–93	60–106		64–107	60–106
Pulse	Mean ± SD	72.6 ± 11.3	76.5 ± 12.9	0.155	72.5 ± 10.8	75.8 ± 12.8	0.195
(bpm)	Med	74.0	77.0		74.0	74.5
	Min–Max	45–103	55–112		45–103	55–112

PPS, Per protocol set; SAF, Safety analysis population; n, number; SD, standard deviation; Med, median; Min, minimum; Max, maximum; BMI, Body mass index; PBF, percentage body fat; BP, Blood pressure; ¹ Age and K-L grade were compared between groups using the Chi-square test. Other items were compared between groups using Welch’s t-test.