Table 1.
Overview of included protocols assessed using SPIRIT statement
| 1st Author | Country | Year | Journal | Trial name | Trial phase | Tumor type | |
|---|---|---|---|---|---|---|---|
| 1 | Michael D Jenkinson | UK | November 2014 | Trials | The ROAM/EORTC-1308 trial: Radiation vs. Observation following surgical resection of Atypical Meningioma | 3 | Atypical Meningioma |
| 2 | Michelle J Naughton | USA | May 2018 | Neuro Oncology Practice | Quality of life of irradiated brain tumor survivors treated with donepezil or placebo: Results of the WFU CCOP research base protocol 91105 | 3 | Any primary or metastatic brain tumor |
| 3 | Georgia K B Halkett | Australia | October 2015 | BMJ Open | Protocol for the Care-IS Trial: A randomized controlled trial of a supportive educational intervention for carers of patients with high-grade glioma (HGG) | 3 | High-Grade Glioma |
| 4 | Robert Olson | Canada | May 2020 | BMC Cancer | Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): Study protocol for a randomized phase III trial | 3 | Oligometastatic tumors |
| 5 | David A Palma | Canada | August 2019 | BMC Cancer | Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): Study protocol for a randomized phase III trial | 3 | Oligometastatic tumors |
| 6 | Lin Kong | China | February 2019 | Cancer Communications London | Carbon ion radiotherapy boost in the treatment of glioblastoma: A randomized phase I/III clinical trial | Phase 1/3 | Glioblastoma |
| 7 | Jaap D Zindler | Netherlands | July 2017 | BMC Cancer | Whole brain radiotherapy versus stereotactic radiosurgery for 4–10 brain metastases: a phase III randomized multicentre trial | 3 | 4–10 Brain Metastases |