Table 3.
Targetable Fusions Identified
| Targetable Gene Partner | Variant | Total Number of Fusions |
|---|---|---|
| FGFR3 |
FGFR3::TACC3 (n = 4) FGFR3::BRAP (n = 1) FGFR3::RENBP (n = 1) |
16 |
| MET |
PTPRZ1::MET (n = 5) CAPZA2::MET (n = 3) ST7::MET (n = 3) KLF12::MET (n = 1) MET exon 14 skip (n = 1) TRIM24::MET (n = 1) |
14 |
| EGFR | EGFR::SEPT14 (n = 7) | 7 |
| BRAF |
KIAA1549::BRAF (n = 4)
BRAF::LHFPL3 (n = 1) PRKAR2B::BRAF (n = 1) |
6 |
| NTRK2 |
BCR::NTRK2 (n = 2)
STRN::NTRK2 (n = 1) PDE5A::NTRK2 (n = 1) SKAP2::NTRK2 (n = 1) |
5 |
| NTRK1 |
ARHGEF2::NTRK1 (n = 1)
BCAN::NTRK1 (n = 1) |
2 |
| ROS 1 |
GOPC::ROS1 (n = 3)
DLL1::ROS1 (n = 1) |
4 |
| PIK3CA | ACAP2::PIK3CA (n = 1) | 1 |
| Total | 55 |