Table 6.

Association between vitamin D treatment and clinical outcomes stratified by age, gender, and presence of septic shock, CHF, AKI, CKD, and osteoporosis.

	Number of Patients	OR for in-Hospital Mortality	HR for 28-Day Mortality	HR for 90-Day Mortality	p-Values for Interaction
Age					0.08
>60	2421	0.57 (0.42–0.79)	0.62 (0.46–0.82)	0.67 (0.49–0.93)
<60	1118	1.01 (0.58–1.76)	0.85 (0.46–1.57)	1.10 (0.64–1.88)
Gender					0.75
Male	1573	0.65 (0.44–0.96)	0.63 (0.44–0.90)	0.71 (0.52–0.98)
Female	1966	0.63 (0.42–0.96)	0.63 (0.43–0.93)	0.68 (0.48–0.97)
Septic shock					0.10
Yes	2043	0.60 (0.41–0.86)	0.62 (0.45–0.86)	0.67 (0.47–0.86)
No	1496	0.88 (0.56–1.37)	0.84 (0.53–1.34)	1.06 (0.70–1.60)
CHF					0.53
Yes	749	0.56 (0.31–0.99)	0.56 (0.33–0.95)	0.60 (0.37–0.98)
No	2790	0.70 (0.50–0.91)	0.67 (0.50–0.91)	0.75 (0.58–0.99)
AKI					0.80
Yes	2257	0.70 (0.50–0.98)	0.68 (0.50–0.92)	0.76 (0.58–0.99)
No	1282	0.55 (0.32–0.95)	0.58 (0.35–0.96)	0.62 (0.39–0.99)
CKD					0.53
Yes	858	0.56 (0.32–0.99)	0.57 (0.34–0.96)	0.62 (0.38–0.99)
No	2681	0.71 (0.51–0.99)	0.67 (0.50–0.91)	0.72 (0.55–0.95)
osteoporosis					0.75
Yes	208	0.35 (0.15–0.79)	0.37 (0.17–0.82)	0.42 (0.21–0.85)
No	3331	0.69 (0.51–0.94)	0.68 (0.52–0.90)	0.75 (0.59–0.97)

CHF, chronic heart failure; CKD, chronic kidney disease; AKI, acute kidney injury. The data are presented as the median (25 to 75 percentiles).