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. 2023 Jun 29;17:1176253. doi: 10.3389/fnins.2023.1176253

Figure 5.

Figure 5

Lost neurons lost, new neurons gained, and stable neurons in green ensembles decreased more than stable neurons in blue ensembles increased in connectivity strength of ensembles. (A) Changes in global connectivity strength of lost neurons before and after conditioning. Lost neurons in blue ensembles: −0.027 ± 0.008, n = 370; lost neurons in green ensembles: −0.087 ± 0.007, n = 366. One sample t-test, p < 0.001 in lost neurons in blue ensembles; one sample t-test, p < 0.001 in lost neurons in green ensembles; Mann–Whitney test, p < 0.001 in lost neurons in blue ensembles vs. lost neurons in green ensembles. (B) Changes in global connectivity strength of new neurons before and after conditioning. New neurons in blue ensembles: 0.141 ± 0.008, n =274; new neurons in green ensembles: 0.081 ± 0.010, n = 331. One sample t-test, p < 0.001 in new neurons in blue ensembles; one sample t-test, p < 0.001 in new neurons in green ensembles; Mann–Whitney test, p = 0.001 in new neurons in blue ensembles vs. new neurons in green ensembles. (C) Changes in global connectivity strength of stable neurons before and after conditioning. Stable neurons in blue ensembles: 0.045 ± 0.006, n = 386, stable neurons in green ensembles: −0.016 ± 0.006, n = 425. One sample t-test, p < 0.001 in stable neurons in blue ensembles; one sample t-test, p = 0.016 in stable neurons in green ensembles; Mann–Whitney test, p < 0.001 in stable neurons in blue ensembles vs. stable neurons in green ensembles. The median, quarterlies, and 95% of confidence interval are illustrated in the box charts. #represents the significant level compared to zeros #p < 0.05, ##p < 0.01, ###p < 0.001, and ***p < 0.001.