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. 2023 Jun 29;10:1191354. doi: 10.3389/fmed.2023.1191354

Table 2.

Details of GO terms and KEGG pathway enrichment in GSE211378.

Ontology ID Description GeneRatio BgRatio p value p. Adjust
BP GO:0019221 Cytokine-mediated signaling pathway 107/298 486/18800 1.85e-94 7.49e-91
BP GO:0001819 Positive regulation of cytokine production 73/298 475/18800 3.89e-51 7.86e-48
BP GO:0070661 Leukocyte proliferation 59/298 330/18800 5.31e-45 7.16e-42
BP GO:0070663 Regulation of leukocyte proliferation 50/298 254/18800 3.08e-40 3.12e-37
BP GO:0070665 Positive regulation of leukocyte proliferation 42/298 158/18800 1.04e-39 8.4e-37
CC GO:0009897 External side of plasma membrane 47/299 455/19594 1.46e-25 4.82e-23
CC GO:0030667 Secretory granule membrane 27/299 312/19594 3.65e-13 6.01e-11
CC GO:0098857 Membrane microdomain 27/299 327/19594 1.12e-12 1.23e-10
CC GO:0045121 Membrane raft 26/299 326/19594 6.56e-12 5.4e-10
CC GO:0098802 Plasma membrane signaling receptor complex 25/299 313/19594 1.64e-11 1.08e-09
MF GO:0005126 Cytokine receptor binding 60/298 272/18410 5.35e-51 2.8e-48
MF GO:0005125 Cytokine activity 48/298 235/18410 5.11e-39 1.34e-36
MF GO:0004896 Cytokine receptor activity 33/298 97/18410 4.62e-35 6.82e-33
MF GO:0140375 Immune receptor activity 38/298 148/18410 5.22e-35 6.82e-33
MF GO:0048018 Receptor ligand activity 50/298 489/18410 7.6e-26 7.95e-24
KEGG hsa04060 Cytokine-cytokine receptor interaction 80/260 295/8164 9.7e-55 2.45e-52
KEGG hsa05417 Lipid and atherosclerosis 48/260 215/8164 4.95e-28 6.26e-26
KEGG hsa04630 JAK–STAT signaling pathway 42/260 162/8164 2.38e-27 2.01e-25
KEGG hsa04061 Viral protein interaction with cytokine and cytokine receptor 34/260 100/8164 1.35e-26 8.55e-25
KEGG hsa04659 Th17 cell differentiation 34/260 108/8164 2.53e-25 1.28e-23