Table 4. FNA recommendations of the 2020 C-TIRADS, 2017 ACR-TIRADS and 2015 ATA guidelines.
| Parameter | C-TIRADS | ACR-TIRADS | ATA guidelines | P value | ||
|---|---|---|---|---|---|---|
| C-TIRADS vs. ACR-TIRADS | C-TIRADS vs. ATA guidelines | ACR-TIRADS vs. ATA guidelines | ||||
| Sensitivity (%) | 84.25 | 57.53 | 62.67 | <0.001 | <0.001 | 0.21 |
| Specificity (%) | 58.76 | 42.94 | 13.25 | <0.001 | <0.001 | <0.001 |
| PPV (%) | 38.92 | 23.93 | 18.39 | <0.001 | <0.001 | 0.006 |
| NPV (%) | 92.28 | 76.43 | 53.22 | <0.001 | <0.001 | <0.001 |
| Accuracy (%) | 64.82 | 46.42 | 25.00 | <0.001 | <0.001 | <0.001 |
C-TIRADS, Chinese Thyroid Imaging Reporting and Data System; ACR-TIRADS, Thyroid Imaging Reporting and Data System of the American College of Radiology; ATA guidelines, American Thyroid Association guidelines; AUROC, area under the receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value; FNA, fine needle aspiration.