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. 2023 Jun 30;10:1153926. doi: 10.3389/fcvm.2023.1153926

Table 3.

Trends in glycemic, blood pressure, and lipids control among US adultsa.

Weighted Prevalence (95% Confidence Interval), %b Absolute
2001–2004 2005–2008 2009–2012 2013–2016 2017–2020 P trendc changed, %
Diabetes (n = 4,559)
Diagnostic rate 82.2 (78.5–85.9) 79.4 (74.7–84.1) 82.1 (78.6–85.7) 88.1 (85.1–91.0) 84.6 (81.4–87.8) 0.009 2.4 (−2.5 to 7.2)
Medicine for diabetes 64.4 (60.3–68.5) 66.5 (61.5–71.5) 69.1 (66.2–71.9) 75.9 (72.9–78.9) 73.7 (70.3–77.1) <0.001 9.3 (4.0 to 14.6)
HbA1c < 8% 75.0 (70.8–79.3) 78.5 (74.8–82.3) 76.9 (72.8–81.0) 73.2 (69.7–76.7) 77.7 (72.9–82.5) 0.814 2.6 (−3.8 to 9.0)
HbA1c < 7% 56.7 (52.5–61.0) 55.5 (50.0–60.9) 54.1 (49.1–59.1) 52.3 (48.1–56.5) 57.7 (51.6–63.7) 0.828 0.9 (−6.5 to 8.3)
Hypertensione (n = 12,072)
Diagnostic rate 78.0 (75.4–80.6) 82.3 (80.4–84.3) 83.6 (81.3–85.8) 85.2 (83.3–87.0) 80.4 (77.7–83.2) 0.022 2.4 (−1.4 to 6.3)
Medicine for hypertension 59.9 (56.1–63.6) 63.9 (61.5–66.3) 67.2 (64.0–70.3) 65.7 (62.5–69.0) 64.8 (62.3–67.4) 0.018 5.0 (0.4 to 9.5)
BP < 140/90 mmHg 46.6 (43.4–49.9) 55.2 (52.6–57.9) 59.9 (57.4–62.4) 58.3 (54.7–62.0) 55.1 (52.1–58.1) <0.001 8.5 (4.0 to 12.9)
BP < 130/80 mmHg 25.7 (23.0–28.4) 32.4 (29.3–35.5) 38.8 (35.7–41.8) 36.2 (33.0–39.4) 36.3 (33.2–39.5) <0.001 10.6 (6.5 to 14.7)
Dyslipidemiaf (n = 16,139)
Diagnostic rate 58.4 (55.4–61.4) 63.4 (61.3–65.6) 65.2 (62.8–67.7) 69.9 (67.7–72.2) 71.0 (67.6–74.4) <0.001 12.6 (8.1 to 17.1)
Medicine for dyslipidemia 26.3 (24.0–28.6) 34.7 (32.3–37.2) 36.5 (34.3–38.7) 36.6 (34.4–38.9) 36.6 (32.5–40.6) <0.001 10.3 (5.6 to 14.9)
Non-HDL-C < 130 mg/dl 16.3 (14.3–18.2) 24.4 (22.6–26.3) 27.4 (25.1–29.7) 31.4 (29.3–33.6) 32.9 (28.6–37.2) <0.001 16.6 (11.9 to 21.4)
HDL-C ≥ 60 mg/dl 22.7 (20.7–24.7) 24.3 (22.6–26.0) 22.7 (20.1–25.3) 26.5 (24.0–28.9) 25.1 (22.3–27.8) 0.049 2.4 (−1.0 to 5.8)
Recommend stating (n = 10,689)
Prevalence of statin use 20.0 (18.0–21.9) 28.3 (25.9–30.7) 30.8 (28.0–33.6) 36.3 (33.6–39.0) 36.4 (32.2–40.7) <0.001 16.5 (11.8 to 21.2)
TC < 200 mg/dl 36.1 (34.0–38.2) 42.4 (39.8–45.1) 48.8 (45.3–52.3) 50.1 (47.9–52.3) 55.4 (50.1–60.8) <0.001 19.4 (13.6 to 25.1)
LDL-C < 100 mg/dl 19.5 (16.9–22.0) 31.3 (28.6–34.1) 34.2 (30.7–37.8) 38.2 (35.6–40.8) 40.3 (35.6–45.0) <0.001 20.9 (15.5 to 26.2)

BP, blood pressure; non-HDL, non-high density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; ASCVD, atherosclerotic cardiovascular disease.

a

Participants aged 40–79 years without clinical ASCVD and all variables of the Pooled Cohort Equations were included. Diagnosed diabetes, hypertension, and dyslipidemia were defined as self-reported diagnosis or taking drugs. To convert TC, LDL-C, HDL-C, and non-HDL-C to mmol/l, multiply values by 0.0259. To convert triglycerides to mmol/l, multiply values by 0.0113.

b

Estimates were age- and sex-adjusted by the direct method to the 2017–2018 NHANES adults without pre-existing ASCVD.

c

The statistical significance of a linear trend was assessed using the weighted regression and modeling the midpoint of each time period.

d

Indicates the absolute increase in prevalence of glycemic, blood pressure, and lipid control between 2001 and 2004 and 2017 to 2020. Values are percentages (95% CIs).

e

Hypertension was defined as a self-reported diagnosis of hypertension, currently taking antihypertensive drugs, or diagnosed as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg.

f

Dyslipidemia was defined as at least one abnormality in TC, LDL-C, TG, or HDL-C or self-reported diagnosis of high cholesterol level or taking lipid-lowering drugs.

g

Recommend statin was defined as (1) LDL > 190 mg/dl or (2) one or more CVD risk factors (i.e., dyslipidemia, diabetes, hypertension, or smoking) with projected 10-year ASCVD risk ≥7.5%.