Table 2.
Univariate and multivariate logistic regression analyses of 30-day mortality in the training cohort.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Characteristic | OR (95%CI) | P value | Characteristic | OR (95%CI) | P value |
| Male | 1.759 (0.962, 3.216) | 0.067 | Male | ||
| Age ≥60 years | 0.728 (0.357, 1.487) | 0.384 | Age ≥60 years | ||
| Pathogens | – | 0.999 | Pathogens | ||
| Gram-negative bacteria | Gram-negative bacteria | ||||
| Gram-positive bacteria | Gram-positive bacteria | ||||
| Fungi | Fungi | ||||
| Septic shock | 8.078 (4.248, 15.358) | <0.001 | Septic shock | 6.548 (3.042, 14.092) | <0.001 |
| Relapsed/refractory HMs | 1.979 (1.116, 3.511) | 0.02 | Relapsed/refractory HMs | 2.811 (1.317, 6.002) | 0.008 |
| Hematopoietic stem cell transplantation | 1.392 (0.532, 3.644) | 0.501 | Hematopoietic stem cell transplantation | ||
| Nosocomial infection | 1.951(0.712, 5.347) | 0.194 | Nosocomial infection | ||
| Length of stay before BSI, days | 1.017 (1.005, 1.030) | 0.007 | Length of stay before BSI, days | 0.055 | |
| Concurrent pulmonary infection | 3.858 (1.130, 13.177) | 0.031 | Concurrent pulmonary infection | 0.238 | |
| Concurrent intestinal infection | 0.938 (0.352, 2.500) | 0.897 | Concurrent intestinal infection | ||
| Concurrent perianal infection | 2.186 (1.022, 4.674) | 0.044 | Concurrent perianal infection | 0.233 | |
| White blood cell count, 109/l | 0.955 (0.977, 1.012) | 0.555 | White blood cell count, 109/l | ||
| Neutropenia | 2.569 (1.143, 5.774) | 0.022 | Neutropenia | 0.190 | |
| Profound neutropenia | 1.213 (0.674, 2.183) | 0.519 | Profound neutropenia | ||
| Albumin <30g/l | 5.691 (3.153, 10.272) | <0.001 | Albumin <30g/l | 7.640 (3.529, 16.542) | <0.001 |
| PCT, ng/ml | 1.010 (0.997, 1.022) | 0.137 | PCT, ng/ml | ||
| CRP, mg/l | 1.003 (1.000, 1.007) | 0.055 | CRP, mg/l | ||
| Platelets <30×109/l before BSI | 6.422 (2.789, 14.788) | <0.001 | Platelets <30×109/l before BSI | 9.761 (3.511, 27.132) | <0.001 |
| Platelets <30×109/l after BSI | 3.948 (1.701, 9.166) | 0.001 | Platelets <30×109/l after BSI | 0.312 | |
| Placement of urinary catheter | 3.729 (1.845, 7.537) | <0.001 | Placement of urinary catheter | 0.274 | |
| Placement of PICC/CVC | 0.875 (0.506, 1.512) | 0.632 | Placement of PICC/CVC | ||
| Secondary DIC | 6.422 (2.789, 14.788) | <0.001 | Secondary DIC | 0.124 | |
| BSI with MDR bacteria | 1.109 (0.638, 1.927) | 0.714 | BSI with MDR bacteria | ||
| Inappropriate empiric antibiotic treatment | 2.044 (1.163, 3.590) | 0.013 | Inappropriate empiric antibiotic treatment | 3.213 (1.522, 6.785) | 0.002 |
| Combined empiric antibiotic treatment | 3.136 | 0.003 | Combined empiric antibiotic treatment | 0.214 | |
| Chemotherapy regimen containing glucocorticoid | 2.093 (1.202, 3.645) | 0.009 | Chemotherapy regimen containing glucocorticoid | 0.410 | |
The bold values means “p<0.05”. A p <0.05 was statistically significant.