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. 2023 Jun 30;14:1169707. doi: 10.3389/fneur.2023.1169707

Table 3.

Performance of the machine-learning algorithm.

Comparisons Speech-task Assoc. criterion Youden index Se (%) Sp (%) PPV (%) NPV (%) Acc (%) AUC
PWS vs. C Vowel −0.24 0.75 88.7 86.3 90.0 84.6 87.7 0.934
S1 0.12 0.66 85.7 80.8 85.7 80.8 83.6 0.906
S2 −0.09 0.62 81.3 80.9 87.1 73.1 81.1 0.881
cC vs. cPWS Vowel 0.23 0.94 93.8 100 100 90.0 96.0 0.993
S1 0.06 0.85 90.6 94.4 96.7 85.0 92.0 0.970
yC vs. yPWS Vowel 0.66 0.80 92.3 87.9 90.0 90.6 90.3 0.975
S1 0.07 0.81 88.4 93.1 95.0 84.4 90.3 0.973
cC vs. yC Vowel 0.39 0.88 93.3 95.5 93.3 95.5 94.3 0.991
S1 0.43 0.94 96.7 97.5 96.7 97.5 97.1 0.998
cPWS vs. yPWS Vowel 0.20 0.86 94.4 91.2 85.0 96.9 92.3 0.956
S1 0.24 0.89 100 88.9 80.0 100 92.3 0.933

C, the whole group of controls; cC, controls in prepubertal age; yC, younger adult controls in postpubertal age; PWS, the whole group of people with stuttering; cPWS, children people with stuttering in the prepubertal age; yPW, younger adult people with stuttering in the postpubertal age; Acc, accuracy; AUC, area under the curve; NPV, negative predictive value; PPV, positive predictive value; Se, sensitivity; Select Sent., selective sentence which consists of the emission of the sentence of the connected speech supposed to induce stuttering in patients; Sp, specificity; Stand. Sent., standard sentence which is the sentence of the connected speech used in our previous papers in the field of voice analysis. Instances refer to the number of subjects considered in each comparison. Cross-validation refers to standardized procedures of a machine-learning algorithm (see the text for details).