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. 2023 Jul 11;11(7):e006788. doi: 10.1136/jitc-2023-006788

Figure 2.

Figure 2

Prediction performance of preCIRI14 model using baseline circulating cytokine signature. (A) Feature cytokines selected using random survival forest (RSF) minimal depth filter: the importance score was defined as 1/(minimal depth); (B) Concordance (C)-indices of preCIRI14 model for the training and validation sets; time-dependent area under the curve AUC of receiver operating characteristic curves (ROCs) at each time point for the (C) training and (E) validation sets; overall survival time of ‘high risk’ and ‘low risk’ groups predicted by preCIRI14 for (D) training and (F) validation sets using cut-off value optimized by training set (see online supplemental figure S1). The CIRI scores indicate risk of event occurrence, whereas ‘high risk’ indicates patients with high CIRI scores and ‘low risk’ indicates patients with low CIRI scores.