Table 4.

Multivariate rank-based estimation regression models for relative change (%/year) in thoracic atherosclerotic plaque volume from baseline to follow-up (Scan 0–Scan 1)

	Non-calcified plaque volume		Calcified plaque volume
	Beta	P value	Beta	P value
ICI use	7.9	0.015	−20.7	0.022
Age	−0.2	0.20	0.3	0.59
Female	3.4	0.24	1.9	0.81
Diabetes	−0.2	0.96	−7.5	0.52
Hyperlipidemia	8.5	0.043	19.1	0.10
Hypertension	5.9	0.071	6.7	0.46
Statin	−7.3	0.10	0.6	0.96
History of smoking	−3.5	0.28	−3.1	0.73
Prior radiation	−7.6	0.12	1.5	0.92

ICI, immune checkpoint inhibitor.