Table 2.

Participant timeline

Item	Screening/ baseline		Final visit
	Visit 1	Visit 2	Visit 3
Date	H0	H24	H48
Eligibility: check inclusion and exclusion criteria	X
Informed consent	X
Inclusion and randomisation	X
Demography	X
Medical history	X
Clinical evaluation*	X	X	X
Arterial blood gases†	X	X	X
Endpoint evaluation/physiological measures	X	X	X
Status of extubation success	X	X	X
Adverse events recording	X	X	X

*Includes haemodynamic, respiratory and ventilatory parameters.

†As usually performed for the daily patient care if an arterial catheter was in place. Supplementary blood gases could be done according to the clinical state of the patient.