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. 2023 Jun 30;14:1177403. doi: 10.3389/fimmu.2023.1177403

Table 2.

Prognostic significance of inflammation parameters for the overall survival of surgically resectable ovarian cancer.

Variables Univariate Multivariate
HR 95% CI P value HR 95% CI P value
Age (>55 vs.≤55) 1.242 1.008-1.530 0.042 0.956 0.686-1.332 0.791
Menopause (No vs. Yes) 1.336 1.079-1.655 0.008 1.373 0.979-1.925 0.066
FIGO stage
I 0.426 0.210-0.867 0.019 0.449 0.219-0.917 0.028
II 0.528 0.317-0.880 0.014 0.573 0.343-0.959 0.034
III 1.074 0.796-1.450 0.640 1.029 0.760-1.392 0.856
IV 1.000 1.000
Family history of cancer (No vs. Yes) 0.909 0.727-1.137 0.404
Residual disease (>1cm vs. ≤1cm) 1.584 1.224-2.050 <0.001 1.386 1.066-1.802 0.015
Histology (Other vs. Serous) 1.113 0.846-1.465 0.443
Grade
Well 0.862 0.627-1.185 0.360
Moderate 1.088 0.848-1.396 0.506
Poor 1.000
Lymph node status (Negative vs. Positive) 1.184 0.959-1.462 0.116
CA125 at diagnosis (>35 U/ml vs.≤35 U/ml) 1.389 0.781-2.470 0.264
NLR (≥2.87 vs.<2.87) 1.195 0.968-1.476 0.098
LMR (≥2.73 vs.<2.73) 0.817 0.663-1.006 0.057
PLR (≥182.23 vs.<182.23) 1.235 1.002-1.522 0.047 1.158 0.935-1.434 0.179
SII (≥727.90 vs.<727.90) 1.214 0.983-1.499 0.072
PNR(≥24.65 vs.<24.65) 1.320 0.963-1.810 0.085

The bold values represent P<0.05.