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. 2023 Jun 30;14:1177403. doi: 10.3389/fimmu.2023.1177403

Table 3.

Prognostic significance of inflammation parameters for the relapse-free survival of surgically resectable ovarian cancer.

Variables Univariate Multivariate
HR 95% CI P value HR 95% CI P value
Age (>55 vs.≤55) 1.037 0.870-1.236 0.687
Menopause (No vs. Yes) 1.046 0.878-1.247 0.615
FIGO stage
I 0.084 0.034-0.207 <0.001 0.116 0.046-0.290 <0.001
II 0.217 0.131-0.359 <0.001 0.273 0.161-0.461 <0.001
III 0.787 0.631-0.981 0.033 0.812 0.649-1.016 0.069
IV 1.000 1.000
Family history of cancer (No vs. Yes) 0.871 0.722-1.051 0.149
Residual disease (>1cm vs. ≤1cm) 1.599 1.257-2.035 <0.001 1.349 1.058-1.720 0.016
Histology (Other vs. Serous) 0.473 0.356-0.630 <0.001 0.647 0.484-0.865 0.003
Grade
Well 1.151 0.917-1.445 0.226
Moderate 1.202 0.962-1.502 0.106
Poor 1.000
Lymph node status (Negative vs. Positive) 1.584 1.324-1.896 <0.001 1.063 0.882-1.283 0.521
CA125 at diagnosis (>35 U/ml vs.≤35 U/ml) 0.949 0.629-1.430 0.801
NLR (≥2.87 vs.<2.87) 1.127 0.945-1.344 0.184
LMR (≥3.39 vs.<3.39) 0.685 0.568-0.827 <0.001 0.810 0.661-0.992 0.042
PLR (≥181.46 vs.<181.46) 1.235 1.036-1.472 0.018 0.890 0.718-1.104 0.288
SII (≥882.31 vs.<882.31) 1.187 0.997-1.415 0.055
PNR(≥49.20 vs.<49.20) 1.402 1.177-1.670 <0.001 1.351 1.103-1.656 0.004

The bold values represent P<0.05.