Table 3.
Association between baseline characteristics and having a medication review in 2019, Cox regression
| Hazard ratios (95% confidence intervals), p-value | |||
|---|---|---|---|
| Unadjusted | Age-sex adjusted | Fully adjusteda | |
| Age group, years (vs 65-74) | |||
| 75-84 | 1.13 (1.11, 1.15), p<0.001 | 1.13 (1.11, 1.15), p<0.001 | 1.03 (1.02, 1.05), p<0.001 |
| 85-94 | 1.22 (1.19, 1.26), p<0.001 | 1.22 (1.19, 1.26), p<0.001 | 1.04 (1.01, 1.06), p=0.006 |
| 95+ | 1.26 (1.20, 1.32), p<0.001 | 1.26 (1.20, 1.33), p<0.001 | 1.02 (0.97, 1.07), p=0.516 |
| Female vs male | 1.01 (0.99, 1.02), p=0.315 | 0.99 (0.98, 1.01), p=0.304 | 1.00 (0.99, 1.01), p=0.781 |
| Townsend quintile (vs 1 – least deprived) | |||
| Quintile 2 | 0.99 (0.81, 1.21), p=0.935 | 0.99 (0.81, 1.22), p=0.938 | 0.94 (0.80, 1.11), p=0.477 |
| Quintile 3 | 1.03 (0.85, 1.25), p=0.756 | 1.03 (0.85, 1.25), p=0.754 | 0.97 (0.84, 1.12), p=0.678 |
| Quintile 4 | 1.02 (0.82, 1.26), p=0.891 | 1.02 (0.82, 1.26), p=0.870 | 0.96 (0.81, 1.13), p=0.594 |
| Quintile 5 - most deprived | 1.04 (0.84, 1.30), p=0.700 | 1.05 (0.84, 1.30), p=0.669 | 0.98 (0.82, 1.15), p=0.776 |
| Practice region (vs Scotland) | |||
| Wales | 1.01 (0.87, 1.17), p=0.904 | 1.01 (0.87, 1.17), p=0.942 | 0.99 (0.87, 1.13), p=0.913 |
| Northern Ireland | 0.82 (0.64, 1.06), p=0.131 | 0.82 (0.64, 1.06), p=0.128 | 0.81 (0.65, 1.01), p=0.064 |
| London | 0.54 (0.39, 0.74), p<0.001 | 0.53 (0.38, 0.74), p<0.001 | 0.62 (0.47, 0.81), p=0.001 |
| Rest of England | 0.72 (0.58, 0.88), p=0.001 | 0.71 (0.58, 0.87), p=0.001 | 0.77 (0.65, 0.91), p=0.003 |
|
Number of ongoing prescriptions at baseline (vs 1) | |||
| 2-4 | 1.45 (1.42, 1.49), p<0.001 | 1.44 (1.41, 1.48), p<0.001 | 1.27 (1.24, 1.30), p<0.001 |
| 5-9 | 1.88 (1.81, 1.95), p<0.001 | 1.84 (1.77, 1.92), p<0.001 | 1.41 (1.37, 1.46), p<0.001 |
| 10-14 | 2.25 (2.14, 2.37), p<0.001 | 2.20 (2.09, 2.32), p<0.001 | 1.48 (1.43, 1.55), p<0.001 |
| 15-19 | 2.51 (2.35, 2.67), p<0.001 | 2.46 (2.31, 2.63), p<0.001 | 1.51 (1.44, 1.59), p<0.001 |
| 20+ | 2.83 (2.56, 3.13), p<0.001 | 2.81 (2.54, 3.11), p<0.001 | 1.64 (1.49, 1.80), p<0.001 |
| Medication review in previous year | 2.05 (1.89, 2.21), p<0.001 | 2.03 (1.88, 2.20), p<0.001 | 1.83 (1.69, 1.98), p<0.001 |
| Living in a care home | 1.98 (1.83, 2.15), p<0.001 | 1.87 (1.73, 2.03), p<0.001 | 1.51 (1.40, 1.62), p<0.001 |
aAdjusted for variables shown plus baseline diagnoses and clinical indicators, and medicines prescribed in 6 months prior to baseline (see Additional File 2 Table S2.2 for the complete list)