Table 1.

Strengths and Limitations of Current Commercially Available CL Systems During Exercise.

Strengths	Limitations
• Responsive to changes in glucose • Devices are portable • Improved time-in-range during exercise • Most systems are waterproof or water-resistant • Device performance is not significantly impacted by exercise	• Preplanning required due to slow onset and offset of subcutaneously delivered insulin • CGM and cannula site adhesive may be affected by sweat • Inability to automatically recognize exercise versus rest • CGM accuracy can be impacted with rapid changes in glucose during exercise

Abbreviations: CL, closed loop; CGM, continuous glucose monitoring.