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. 2023 Jul 13;55(1):2233425. doi: 10.1080/07853890.2023.2233425

Table 1.

Characteristics of tirofiban.

Drug name Tirofiban
Chemical structure graphic file with name IANN_A_2233425_ILG0001_B.jpg
Chemical name N-(butylsulfonyl)-O-[4- (4-piperidinyl)butyl]-L-tyrosine
Substance type Non-peptide
Inhibition modality Selective competitive
Binding modality Reversible
Route of administration Intravenous
Onset >90% inhibition of platelet aggregation seen within 10 min
Distribution Vdss: 22–42 L
Protein Binding 65%
Plasma Half-life 2h
Platelet function recovery time 4–8 h after discontinuation
Excretion Urine (65%) and feces (25%) primarily as unchanged tirofiban