Table 2. . Factors associated with severe patients infected with COVID-19.
| Factors | ||||
|---|---|---|---|---|
| Baseline predictors | OR (95% CI) | p-value | aOR (95% CI) | p-value |
| Mean age ± SD | – | – | 0.825 (0.792–0.923) | 0.041† |
| LDL (mg/dl) | 1.056 (1.038–1.074) | <0.001† | 0.822 (0.701–0.908) | 0.027† |
| HDL (mg/dl) | – | – | 0.283 (0.170–0.523) | 0.004† |
| Uric acid, mg/dl | 2.863 (2.093–3.917) | <0.001† | 1.163 (1.101–1.722) | <0.001† |
| Creatinine, mg/dl | 0.006 (0.001–0.034) | <0.001† | 1.175 (1.122–1.503) | <0.001† |
| ALT, IU/l | – | – | 0.921 (0.873–0.983) | <0.001† |
| ESR, (mm/1st h) | – | – | 0.914 (0.899–0.992) | 0.002† |
| 25-hydroxyvitamin D, (ng/ml) | 1.070 (1.033–1.108) | <0.001† | 1.153 (1.091–1.410) | <0.001† |
| CRP, (mg/l) | 0.964 (0.947–0.981) | <0.001† | 0.892 (0.810–0.992) | 0.001† |
| Real-time PCR Ct values | 1.175 (1.012–2.217) | 0.021† | 2.215 (1.722–2.925) | <0.001† |
| TRIM56 gene expression | 0.801 (0.727–0.882) | <0.001† | 0.522 (0.470–0.822) | 0.002† |
†
Statistically significant (<0.05).
ALT: Alanine aminotransferase; aOR: Adjusted odds ratio; CI: Confidence interval; Ct: Cycle threshold; ESR: Erythrocyte sedimentation rate; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; SD: Standard deviation.