Table 1: Evolutionary properties of transient ORFs with phenotypes induced by inhibiting translation.
The pN/pS ratio is obtained from nucleotide variation in the ORF among the 1011 S. cerevisiae strains assembled by Peter et al.40 TBLASTN was run for each ORF against genomes in the subphylum Saccharomycotina, excluding the genus Saccharomyces, with an e-value threshold of 10−4.
| ORF Name | Reading frame conservation | pN/pS (p-value) | TBLASTN matches |
|---|---|---|---|
| YBR196C-A | .29 | 1.34 (0.65) | 0 |
| YDL204W-Aa | .20 | 1.25 (0.83) | 0 |
| YGR016C-Aa | .29 | 0.66 (0.36) | 0 |
| YJL077C | .21 | 0.74 (0.19) | 0 |
| YNL040C-Aa | .38 | 0.97 (1.00) | 0 |
| YPR096C | .20 | 1.39 (0.47) | 0 |
a
We assigned this unannotated ORF a systematic name based on SGD conventions.