Figure 1.

The expression level of RPL23AP53 pseudogene in: melanocytes and melanoma cell lines: BRAF WT (MEVO), BRAF V600E (SKMEL28, WM9, and A549), and BRAF V600D (WM115 and WM266) (A), and melanoma patients from the Cancer Genome Atlas (TCGA) database depending on metastasis status and regional nodal metastases status [graphs from the University of ALabama at Birmingham CANcer (UALCAN) database, modified], BRAF mutation status and BRAF expression level. BRAF wild type (WT), BRAF mutated (MUT) and BRAF V600E (c. 1799T>A) subgroups (B); T-test, one way ANOVA with Kruskal-Wallis test and Spearman correlation; solid lines in the boxplots and dashed lines in violin plots represent mean of expression; p < 0.05 considered as significant, ns - no significant, * p ≤ 0.05, ** p ≤ 0.01