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. 2023 Jun 26;28(2):255–270. doi: 10.5603/RPOR.a2023.0030

Table 1.

The expression levels of RPL23AP53 depending on clinicopathological parameters in The Cancer Genome Atlas (TCGA) melanoma patients; p < 0.05 considered as significant

Parameter Group Cases RPL23AP53
Mean ± SEM p-value
Gender Male 290 0.3804 ± 0.05149 0.2386
Female 178 0.3172 ± 0.06585
Age ≤ 58 236 0.344 ± 0.05770 0.6921
> 58 227 0.3663 ± 0.05737
Ulceration Yes 167 0.3449 ± 0.07375 0.3751
No 147 0.3088 ± 0.06253
Clark level I 6 −0.8354 ± 0.8310 0.2577
II 18 0.4998 ± 0.1706
III 78 0.4666 ± 0.06916
IV 167 0.3722 ± 0.06869
V 53 0.2564 ± 0.1158
Breslow depth < 1.0 51 0.3575 ± 0.08995 0.8240
1.0–2.0 88 0.406 ± 0.08832
2.1–4.0 78 0.4712 ± 0.07299
> 4.0 143 0.3458 ± 0.08105
Mitotic rate <1 3 0.44 ± 0.6814 0.8363
1–4 65 0.369 ± 0.08878
> 4 88 0.3793 ± 0.09413
M Stage M0 418 0.3572 ± 0.04292 0.8753
M1 24 0.3756 ± 0.1354
T Stage T0 23 0.3326 ± 0.1736 0.5480
T1–T2 121 0.3088 ± 0.07192
T3–T4 244 0.383 ± 0.05653
Cancer Type Cutaneous melanoma 69 0.3008 ± 0.1088 0.3570
Desmoplastic melanoma 3 0.826 ± 0.3703
Melanoma 28 0.1691 ± 0.1249
Acral melanoma 2 0.627 ± 0.4657
Lentigo maligna melanoma 1 1.186 ± 0.0
Neoplasm disease stage 0 6 −0.8765 ± 0.8283 0.1866
I–II 218 0.3859 ± 0.05387
III–IV 194 0.3584 ± 0.06433

SEM — standard error of the mean