Table 3.
Multivariate Cox Regression Analysis of Clinicopathological Characteristics
| Clinicopathological Features | β | SE | Wald x2 | HR (95% CI) | P |
|---|---|---|---|---|---|
| aCCI | 2.489 | 0.288 | |||
| <3* | |||||
| 3∼6 | 0.125 | 0.229 | 0.296 | 1.133(0.723~1.775) | 0.587 |
| >6 | 0.445 | 0.294 | 2.289 | 1.561(0.877~2.778) | 0.130 |
| Borrmann type | 3.295 | 0.348 | |||
| TypeI* | |||||
| TypeII | 0.053 | 0.459 | 0.013 | 1.055(0.429~2.592) | 0.908 |
| TypeIII | 0.188 | 0.454 | 0.171 | 1.207(0.496~2.936) | 0.679 |
| TypeIV | 0.308 | 0.459 | 0.452 | 1.361(0.554~3.345) | 0.501 |
| PLR | |||||
| ≤165.12* | |||||
| >165.12 | 0.626 | 0.24 | 6.801 | 1.87(1.168~2.992) | 0.009 |
| ypT stage | 4.124 | 0.007 | |||
| ypT0* | |||||
| ypT1 | 0.092 | 0.355 | 0.004 | 1.178(0.488~1.96) | 0.951 |
| ypT2 | 0.117 | 0.362 | 3.743 | 1.197(0.244~1.999) | 0.053 |
| ypT3 | 0.226 | 0.315 | 0.517 | 1.254(0.677~2.324) | 0.472 |
| ypT4 | 0.315 | 0.365 | 0.743 | 1.37(0.67~2.802) | 0.389 |
| ypN stage | 14.357 | 0.000 | |||
| ypN0* | |||||
| ypN1 | 0.024 | 0.332 | 0.005 | 1.024(0.534~1.962) | 0.943 |
| ypN2 | 0.913 | 0.357 | 6.52 | 2.491(1.236~5.019) | 0.011 |
| ypN3 | 0.967 | 0.47 | 4.233 | 2.63(1.047~6.607) | 0.040 |
| Lymph node positive rate | |||||
| ≤15.72* | |||||
| >15.72 | 0.732 | 0.711 | 1.061 | 2.08(0.516~8.38) | 0.303 |
| TRG | 19.659 | 0.000 | |||
| TRG 0* | |||||
| TRG 1 | 0.21 | 0.491 | 0.183 | 1.234(0.471~3.234) | 0.669 |
| TRG 2 | 0.812 | 0.407 | 3.984 | 2.252(1.015~4.999) | 0.046 |
| TRG 3 | 1.298 | 0.325 | 15.913 | 3.661(1.935~6.926) | 0.000 |
Note: *Is for reference.
Abbreviations: aCCI, age-adjusted Charlson Comorbidity Index; PLR, platelet/lymphocyte ratio; TRG, tumor regression grade; HR, Hazard Rate; CI, confidence interval; SE, Standard Error.